Ehrlichia canis Infection Induced Chronic Kidney Disease in a Labrador Retriever and Its Management: A Case Report
Asian Journal of Research in Animal and Veterinary Sciences,
Page 1-5
Abstract
Introduction: Chronic kidney disease is irreversible, progressive and most common form of kidney disease in dogs. Canine ehrlichiosis is caused by gram negative intracellular bacteria Ehrlichia canis.
Case Presentation: A 7-year old Labrador retriever male dog weighing around 35 kg was presented to the Madras Veterinary College Teaching Hospital with a history of inappetence, vomiting, polyuria and polydipsia from fifteen days. The dog was fully vaccinated and dewormed. On general clinical examination, all vital parameters were within normal range except elevated temperature (103.8°F). The hematological findings revealed mild thrombocytopenia and hypochromasia. The serum biochemistry revealed increased creatinine level (3.68 mg/dl). The blood pressure was measured using Doppler device which revealed secondary hypertension. A blood smear examination was found to be negative.
Case Discussion: The animal was treated for chronic kidney failure. Even then animal was going down and not taking feed. The blood sample was sent for Molecular PCR which confirmed presence of Ehrlichia canis. Then animal was treated for Canine Monocytic Ehrlichiosis to control Ehrlichia canis induced renal failure. Then there was little progress in condition of the animal. The animal was maintained with a renal diet.
Keywords:
- Chronic kidney disease
- Ehrlichia canis
- labrador retriever
- molecular PCR
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References
Suwanpakdee, Namphung Suemanotham1 Sarin. The concurrence of naturally occurring Ehrlichia canis infection and renal dysfunction in dogs: kidney diseases and survival analysis. Journal of Applied Animal Science. 2018;11(3):47-56.
Pinho Flaviane A, Maria G, Prianti, Juliana FV Braga, Lidiany V. Pires, Sílvia A. França, Silvana MMS Silva. Renal histopathological changes in dogs naturally infected with Ehrlichia canis. Braz J Vet Pathol. 2016;9(1):2-15.
IRIS. International Renal Interest Society (IRIS); 2012.
Available:http://www.iris-kidney.com/index.shtml. Novartis Animal Health Inc.; 2007. Accessed March 8, 2012.
Nazari, Mojgan, Sue Yee Lim, Mahira Watanabe, Reuben SK Sharma, Nadzariah ABY Cheng, and Malaika Watanabe. Molecular detection of Ehrlichia canis in dogs in Malaysia. PLoS neglected tropical Diseases. 2013;7(1):e1982.
Sood, Pramod, Gunchan Paul, and Sandeep Puri. Interpretation of arterial blood gas.” Indian journal of critical care medicine: peer-reviewed, official publication of Indian Society of Critical Care Medicine. 2010;14(2):57.
McGrotty, Yvonne. Diagnosis and management of chronic kidney disease in dogs and cats. In practice. 2008;30(9):502-507.
Vervloet Marc G, Adriana J. van Ballegooijen. Prevention and treatment of hyperphosphatemia in chronic kidney disease. Kidney international. 2018;93(5):1060-1072.
Mann, Sahiba SK. Uppal SA, Hussain, Singla LD. Diagnosis and management of Ehrlichia canis associated chronic kidney disease (CKD) in three Labrador dogs. SKUAST Journal of Research. 2017;19(1)160-163.
Ziliani, Thaysa Felfili, Alessandra Ramos Castilho, Daiane Poletto, Adriane Jorge Mendonça, Valéria Régia Franco Sousa, Valéria Dutra. Kidney disease in natural infection by Ehrlichia canis in dogs.” Semina: Ciências Agrárias. 2019;40(2):981-986.
Fiocchi EH, Larry D, Cowgill DC, Brown JE, Markovich S, Tucker MA, Labato, Callan MB. The use of darbepoetin to stimulate erythropoiesis in the treatment of anemia of chronic kidney disease in dogs. Journal of Veterinary Internal Medicine. 2017;31(2):476-485.
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